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Table 2 Latent classes obtained from a five-class solution

From: Replication of an empirical approach to delineate the heterogeneity of chronic unexplained fatigue

Class Attributes Class-1 Class-2 Class-3 Class-4 Class-5 Wald p-Value
Number (%) of subjects 97 (25) 92 (24) 77 (20) 76 (20) 44 (11)   
Stomach problems (%) 57 46 25 12 18 39.2 0.000
Concentration difficulty 33 53 5 0 0 29.1 0.000
Fever 22 28 6 7 16 17.6 0.002
Headache 84 79 53 46 77 33.8 0.000
Joint pain 61 71 34 30 0 34.0 0.000
Muscle pain 81 87 44 46 34 46.9 0.000
Nausea 37 44 10 5 18 31.2 0.000
Photophobia 44 63 14 8 0 51.6 0.000
Shortness of breath 22 47 8 0 4 32.0 0.000
Sore throat 52 58 13 13 36 45.0 0.000
Unusual fatigue 70 86 32 8 11 89.6 0.000
Unrefreshing sleep 98 97 45 41 14 63.9 0.000
Sleep problems 94 97 49 46 29 68.4 0.000
Sleepiness (Epworth score) 10 10 5 6 5 58.6 0.000
Depression (Zung score) 53 56 43 39 35 92.4 0.000
Age (years) 42 44 48 51 38 37.6 0.000
BMI (kg/m2) 24 32 32 24 22 85.6 0.000
Neck circumference (cm) 33 37 37 34 32 72.6 0.000
High sensitivity CRP (mg/dL) 0.10 0.42 0.51 0.1 0.08 72.4 0.000
Serum insulin (units?) 3.9 8.9 8.4 3.9 3.7 79.4 0.000
Cortisol index 1.9 1.5 2.0 1.7 2.2 11.1 0.026
Serum bilirubin 0.4 0.4 0.4 0.5 0.4 14.5 0.006
Serum AST 15 16 15 18 15 15.9 0.003
Hemoglobin 13.0 13.4 13.1 13.3 12.6 20.6 0.000
Heart rate (bpm) 68 68 72 64 64 9.8 0.043
Systolic blood pressure 110 124 126 120 108 55.2 0.000
  1. Figures show (%) of total number in a class endorsing a symptom, median score on self-rating scales, or for biological markers, the median value for the respective class. The variables shown in the table are those significantly contributing to the class solution according to the Wald statistic. BMI = Body Mass Index. CRP = C reactive protein. AST = Aspartate transaminase.