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Table 2 Distribution of medicinal products authorized for human use by therapeutic area (1995-2009) and burden of disease (as measured by disability-adjusted life years and mortality)

From: Does the development of new medicinal products in the European Union address global and regional health concerns?

Disease conditions Medicinal products for human use, 1995-2009 Burden of disease in the population
  Marketing authorizations NCEs Mortality per 106(%) DALYs per 106(%)
  Number (%) Number (%) Worldwide EU-25 Worldwide EU-25
Communicable diseases 100 (19.2) 75 (22.2) 18.0 (30.6) 0.2 (4.8) 604.0 (39.7) 2.7 (4.6)
Infectious and parasitic diseases 68 (13.1) 56 (16.6) 9.5 (16.2) .06 (1.3) 302.1 (19.8) 0.9 (1.6)
Respiratory infections 19 (3.6) 8 (2.4) 4.3 (7.2) 0.1 (3.1) 97.8 (6.4) 0.6 (1.0)
Maternal conditions 11 (2.1) 9 (2.7) 0.5 (0.9) .00 (0.0) 38.9 (2.6) 0.2 (0.3)
Perinatal conditions 2 (0.4) 2 (0.6) 3.2 (5.4) .01 (0.3) 126.4 (8.3) 0.6 (1.0)
Noncommunicable diseases 419 (80.6) 262 (77.5) 35.0 (59.6) 4.0 (89.9) 731.6 (48.0) 51.1 (87.4)
Malignant neoplasms 73 (14.0) 59 (17.5) 7.4 (12.6) 1.2 (27.0) 77.8 (5.1) 9.7 (16.6)
Other neoplasms 1 (0.2) 1 (0.3) 0.2 (0.3) .03 (0.8) 1.9 (0.1) 0.2 (0.3)
Diabetes mellitus 46 (8.8) 25 (7.4) 1.1 (1.9) 0.1 (2.3) 19.7 (1.3) 1.5 (2.5)
Blood and endocrine disorders 59 (11.3) 43 (12.7) 0.3 (0.5) .03 (0.7) 10.4 (0.7) 0.7 (1.3)
Neuropsychiatric conditions 66 (12.7) 37 (10.9) 1.3 (2.1) 0.2 (4.8) 199.3 (13.1) 14.3 (24.5)
Sense organ diseases 11 (2.1) 10 (3.0) 0.0 (0.0) 0.0 (0.0) 86.9 (5.7) 4.4 (7.5)
Cardiovascular diseases 75 (14.4) 29 (8.6) 17.1 (29.0) 1.8 (42.0) 151.4 (9.9) 10.2 (17.4)
Respiratory diseases 11 (2.1) 6 (1.8) 4.0 (6.9) 0.2 (4.9) 59.0 (3.9) 3.1 (5.4)
Digestive diseases 10 (1.9) 4 (1.2) 2.0 (3.5) 0.2 (4.8) 42.5 (2.8) 2.7 (4.6)
Genitourinary diseases 23 (4.4) 13 (3.8) 0.9 (1.6) .07 (1.6) 14.7 (1.0) 0.5 (0.8)
Skin diseases 7 (1.3) 7 (2.1) .07 (0.1) 0.0 (0.2) 4.0 (0.3) 0.1 (0.2)
Musculoskeletal diseases 31 (6.0) 24 (7.1) 0.1 (0.2) .02 (0.5) 30.9 (2.0) 2.6 (4.4)
Congenital anomalies 5 (1.0) 3 (0.9) 0.4 (0.7) .01 (0.3) 25.3 (1.7) 0.6 (1.0)
Oral conditions 1 (0.2) 1 (0.3) 0.0 (0.0) 0.0 (0.0) 7.9 (0.5) 0.4 (0.7)
Unintentional injuries (poisoning) 1 (0.2) 1 (0.3) 0.3 (0.6) .01 (0.2) 7.5 (0.5) 0.2 (0.3)
Total 520 (100) 338 (100) 58.8 (100) 4.4 (100) 1,523.2 (100) 58.4 (100)
  1. Data do not sum to 100% because of rounding errors. Burden of disease data are from World Health Organization 2009 for the year 2004. Burden of disease is measured by mortality and disability-adjusted life years (DALYs). NCEs = New chemical entities. EU-25 = all 25 EU countries in 2004