Using verbal autopsy to assess the prevalence of HIV infection among deaths in the ART period in rural Uganda: a prospective cohort study, 2006-2008

Table 3 Performance of the verbal autopsy tool using HIV serostatus as gold standard, by age group

	Age group (years)
	13-44	45-64	65+	All ages
Specificity (95% CI)	76.5% (62.5-87.2%)	90.0% (76.3-97.2%)	96.5% (91.3-99.0%)	90.2% (85.3-93.9%)
Positive predictive value (95% CI)	72.7% (57.2-85.0%)	77.8% (52.4-93.6%)	33.3% (4.3-77.7%)	70.6% (58.3-81.0%)
HIV-attributable mortality fraction (95% CI)
this study	50.6% (39.6-61.5%)	30.5% (19.2-43.9%)	5.1% (1.9-10.7%)	25.8% (20.6-31.5%)
cohort (based on ALPHA data²)	40.3%	24.4%	1.6%	17.0%

¹Test (verbal autopsy) positive defined as positive by both assessors, or by 2 out of 3 assessors in case of nonagreement; test negative defined as negative or unknown by both assessors, or by 2 out of 3 assessors in case of nonagreement.
²Unpublished Analysing Longitudinal Population-based HIV cohorts in Africa (ALPHA) data