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Table 3 Performance of the verbal autopsy tool using HIV serostatus as gold standard, by age group

From: Using verbal autopsy to assess the prevalence of HIV infection among deaths in the ART period in rural Uganda: a prospective cohort study, 2006-2008

  Age group (years)
  13-44 45-64 65+ All ages
Specificity (95% CI) 76.5% (62.5-87.2%) 90.0% (76.3-97.2%) 96.5% (91.3-99.0%) 90.2% (85.3-93.9%)
Positive predictive value (95% CI) 72.7% (57.2-85.0%) 77.8% (52.4-93.6%) 33.3% (4.3-77.7%) 70.6% (58.3-81.0%)
HIV-attributable mortality fraction (95% CI)     
   this study 50.6% (39.6-61.5%) 30.5% (19.2-43.9%) 5.1% (1.9-10.7%) 25.8% (20.6-31.5%)
   cohort (based on ALPHA data2) 40.3% 24.4% 1.6% 17.0%
  1. 1Test (verbal autopsy) positive defined as positive by both assessors, or by 2 out of 3 assessors in case of nonagreement; test negative defined as negative or unknown by both assessors, or by 2 out of 3 assessors in case of nonagreement.
  2. 2Unpublished Analysing Longitudinal Population-based HIV cohorts in Africa (ALPHA) data