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Table 4 Summary statistics and survey-weighted CVD prevalence by survey-weighted deciles of laboratory biomarkers

From: Multiple biomarker models for improved risk estimation of specific cardiovascular diseases related to metabolic syndrome: a cross-sectional study

 

Summary statistics

Congestive heart failure

Coronary heart disease

Angina

MI

Stroke

 

Range

\( \overline{\mathbf{x}} \) a

95% CIa

n(case/total)

%a

95% CIa

n(case/total)

%a

95% CIa

n(case/total)

%a

95% CIa

n(case/total)

%a

95% CIa

n(case/total)

%a

95% CIa

C-reactive Protein (mg/dL)

All

0.01-29.6

0.417

0.405, 0.429

916/28,817

2.28

2.06, 2.51

1,229/28,778

3.43

3.15, 3.71

921/28,816

2.62

2.33, 2.91

1,296/28,869

3.44

3.15, 3.73

1,055/28,882

2.68

2.42, 2.94

D1

0.01-0.03

0.021

0.020, 0.021

21/2,373

0.73

0.30, 1.16

39/2,371

1.39

0.89, 1.90

32/2,377

1.34

0.77, 1.91

48/2,381

1.39

0.84, 1.95

38/2,381

0.93

0.50, 1.36

D10

0.97-29.6

2.044

1.979, 2.108

202/3,350

5.28

4.37, 6.18*

178/3,343

4.5

3.68, 5.33*

163/3,347

4.41

3.58, 5.24*

222/3,361

5.28

4.42, 6.14*

193/3,362

4.92

4.05, 5.80*

Glycohemoglobin (%)

All

2.00-18.8

5.51

5.49, 5.53

926/29,000

2.30

2.08, 2.53

1,242/28,958

3.44

3.15, 3.72

932/28,999

2.63

2.34, 2.92

1,313/29,051

3.45

3.16, 3.75

1,074/29,066

2.71

2.44, 2.98

D1

2.00-4.83

4.67

4.66, 4.68

21/2,225

0.89

0.42, 1.36

28/2,227

0.87

0.44, 1.29

16/2,227

0.75

0.34, 1.16

34/2,227

1.16

0.63, 1.68

38/2,227

1.44

0.80, 2.08

D10

6.07-18.8

7.34

7.30, 7.42

363/4,390

7.47

6.44, 8.49*

415/4,379

9.69

8.48, 10.91*

315/4,386

7.13

5.94, 8.32*

456/4,409

9.70

8.60, 10.80*

342/4,417

6.98

6.04, 7.93*

Fasting glucose (mg/dL)

All

38.0-587

102.7

102.0, 103.4

377/12,929

2.18

1.87, 2.48

528/12,915

3.38

3.01, 3.74

401/12.920

2.60

2.21, 2.98

578/12,957

3.48

3.08, 3.88

457/12,962

2.70

2.33, 3.07

D1

38.0-84.9

80.4

80.0, 80.7

23/1,272

1.30

0.70, 1.91

23/1,269

1.7

0.77, 2.62

17/1,271

1.24

0.49, 1.99

23/1,274

1.28

0.66, 1.90

27/1,276

1.79

0.94, 2.64

D10

119-587

161.5

157.8, 165.2

119/1,684

6.44

4.76, 8.11*

162/1,683

9.34

7.53, 11.15

132/1,681

7.75

6.00, 9.50*

174/1,691

9.92

7.91, 11.94*

114/1,692

5.80

4.53, 7.06*

Apolipoprotein (B) (mg/dL)

All

24.0-345.0

102.7

93.7, 96.3

211/6,883

2.32

1.88, 2.76

289/6,877

3.46

2.98, 3.93

195/6,877

2.30

1.83, 2.77

324/6,895

3.73

3.18, 4.28

260/6,899

2.83

2.30, 3.36

D1

24.0-63.9

80.4

54.4, 55.8

35/613

4.18

2.27, 6.10

49/611

6.45

4.66, 8.64

24/613

3.33

1.57, 5.09

41/614

6.05

4.02, 8.08

38/616

3.78

2.34, 5.22

D10

127-345

161.5

142.6, 145.6

23/731

2.55

1.15, 3.96

24/733

2.53

1.46, 3.60

11/730

1.14

0.51, 1.78

25/732

2.87

1.52, 4.22

27/733

3.07

1.34, 4.79

Total cholesterol (mg/dL)

All

72.0-727

200.0

199.2, 200.8

909/28,688

2.28

2.06, 2.50

1,224/28,648

3.43

3.15, 3.72

916/28,686

2.60

2.31, 2.89

1,292/28,740

3.44

3.15, 3.73

1,046/28,753

2.67

2.40, 2.93

D1

72.0-150

134.7

134.1, 135.2

206/2,867

4.99

3.96, 6.02

280/2,855

8.44

7.13, 9.76

169/2,868

4.96

3.84, 6.08

244/2,872

6.92

5.79, 8.05

164/2,875

3.87

3.10, 4.63

D10

253-727

280.8

279.2, 282.5

86/3,046

2.12

1.50, 2.73†

106/3,041

3.25

2.53, 3.97†

97/3,044

2.76

2.04, 3.49†

125/3,047

3.34

2.57, 4.12†

119/3,051

3.34

2.49, 4.18

HDL cholesterol (mg/dL)

All

7.0-188

52.7

52.4, 53.1

909/28,686

2.28

2.06, 2.50

1,223/28,646

3.43

3.14, 3.71

916/28,684

2.60

2.31, 2.89

1,291/28,738

3.44

3.15, 3.73

1,045/28,751

2.66

2.39, 2.93

D1

7.0-34.3

30.4

30.2, 30.6

152/2,654

3.95

3.19, 4.71

187/2,652

5.08

4.27, 5.88

122/2,648

3.39

2.65, 4.14

193/2,662

5.32

4.39, 6.24

135/2,659

3.66

2.94, 4.39

D10

73.7-188

85.5

85.0, 86.0

74/3,130

1.93

1.38, 2.47

71/3,126

1.77

1.31, 2.24†

72/3,134

2.10

1.51, 2.69

103/3,133

2.65

1.95, 3.35†

86/3,135

2.03

1.46, 2.61†

LDL cholesterol (mg/dL)

All

21.0-344

118.2

117.3, 119.1

364/12,474

2.18

1.86, 2.50

508/12,459

3.35

2.97, 3.73

383/12,465

2.53

2.15, 2.90

556/12,503

3.51

3.10, 3.91

437/12,506

2.62

2.24, 3.00

D1

21.0-75.0

63.4

62.7, 64.0

90/1,308

5.02

3.76, 6.28

132/1,304

9.25

7.11, 11.38

88/1,309

5.82

4.06, 7.58

119/1,312

7.94

6.26, 9.62

79/1,314

4.13

3.09, 5.16

D10

163-344

185.9

184.2, 187.7

33/1,281

1.72

1.05, 2.39†

37/1,281

1.99

1.29, 2.70†

26/1,276

1.39

0.72, 2.07†

47/1,282

2.46

1.64, 3.27†

46/1,282

3.00

1.78, 4.22

Triglycerides (mg/dL)

All

14.0-3,780

140.7

137.6, 143.9

374/12,788

2.19

1.88, 2.50

524/12,774

3.39

3.02, 3.76

395/12,779

2.57

2.19, 2.95

570/12,817

3.48

3.09, 3.88

449/12,821

2.65

2.28, 3.02

D1

14.0-58.3

47.9

47.3, 48.6

18/1,161

1.08

0.42, 1.74

25/1,161

1.61

0.92, 2.30

18/1,160

1.08

0.58, 1.58

29/1,161

1.90

1.19, 2.61

21/1,161

1.41

0.80, 2.02

D10

237-3,780

382.2

364.8, 399.7

52/1,397

3.26

2.18, 4.33*

76/1,399

5.10

3.63, 6.56*

62/1,397

4.60

3.19, 6.01*

86/1,399

5.74

4.26, 7.22*

57/1,398

3.51

2.49, 4.54*

  1. aSurvey-weighted.
  2. *D10 prevalence significantly higher than D1 prevalence at α = 0.05.
  3. †D10 prevalence significantly lower than D1 prevalence at α = 0.05.