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Table 1 Distribution of cases of CMs, chromosomal abnormalities, and low birth weight rates in the city of Insistence (of the landfill site) and in the Marches Region, 2001 to 2006

From: Application of space-time disease clustering by administrative databases in Italy: Adverse Reproductive Outcomes (AROs) and residential exposure

  Fano Marches
n Rate per 1,000 95 % CI n Rate per 1,000 95 % CI
Congenital malformations
 Central nervous system - - - 23 0.30 0.18–0.44 -
 Cardiovascular 34 9.96 6.89–13.91 980 12.59 11.79–13.43 -
 Orofacial 6 1.76 0.64–3.82 125 1.94 1.33–1.91 -
 Ear 3 0.88 0–5.84 25 0.32 0.07–0.71 -
 Gastrointestinal 4 1.17 0.31–2.99 114 1.77 1.2–1.75 -
 Genitourinary 17 4.98 2.89–7.97 543 6.98 6.49–7.52 -
 Musculoskeletal 24 7.03 4.5–10.45 583 7.51 6.89–8.13 -
 Total 122 35.72 29.66–42.65 3375 43.65 41.88–44.86 -
Chromosomal anomalies 9 2.64 1.14–4.76 86 1.11 0.88–1.36 -
Low birth weight 82 24.05 19.38–29.70 2623 33.71 32.46–35.00 *
Total number of AROsa 301 88.30 78.98–98.32 7894 75.45 73.86–77.07 *
  1. *p < 0.05
  2. aPlease see the Methods section for calculations used