Skip to main content

Table 5 MFI, SF-36 and Symptom Inventory Criteria for CFS - Comparison of CFS Cases identified with Two Methods of Applying the 1994 Case Definition

From: Methods of applying the 1994 case definition of chronic fatigue syndrome – impact on classification and observed illness characteristics

 

CFS Classification (non-overlapping categories)

Criteria

Both Methods

Method 1 Only

Method 2 Only

 

(n=44; M1/M2)

(n=15; only M1)

(n=27; only M2)

(1) MFI Criterion (one of two cutoffs)

   

 (i) General Fatigue ≥ 13*

42 (95.45 %)

9 (60.00 %)

26 (96.30 %)

 (ii) Reduced Activity ≥ 10

34 (77.27 %)

7 (46.67 %)

18 (66.67 %)

 Met at least one*

44 (100 %)

11 (73.33 %)

27 (100 %)

(2) SF-36 Criterion (one of four cutoffs)

   

 (iii) Physical Functioning ≤ 70*

32 (72.73 %)

3 (20.00 %)

14 (51.85 %)

 (iv) Role Physical ≤ 50*

33 (75.00 %)

4 (26.67 %)

19 (70.37 %)

 (v) Social Functioning ≤ 75*

42 (95.45 %)

11 (73.33 %)

25 (92.59 %)

 (vi) Role Emotional ≤ 66.67

29 (65.91 %)

6 (40.00 %)

11 (40.74 %)

 Met at least one*

44 (100 %)

11 (73.33 %)

27 (100 %)

(3) CDC Symptom Criterion (Both cutoffs)

   

 (vii) ≥ 4 CFS Symptoms lasting ≥ 6 months

44 (100 %)

15 (100 %)

27 (100 %)

 (viii) Summary Score ≥ 25*

44 (100 %)

5 (33.33 %)

27 (100 %)

 Met both

44 (100 %)

5 (33.33 %)

27 (100 %)

Meet all criteria (1),(2), (3)

44 (100 %)

0

27 (100 %)

Meets SF-36 Criterion based on Role Emotional Alone

0

0

0

  Total number of criteria (i)-(viii) met (8 maximum)

   

   1

 

1 (6.67 %)

 

   2

 

1 (6.67 %)

 

   3

 

3 (20.00 %)

 

   4

2 (4.55 %)

5 (33.33 %)

1 (3.70 %)

   5

7 (15.91 %)

3 (20.00 %)

7 (25.93 %)

   6

4 (9.09 %)

1 (6.67 %)

8 (29.63 %)

   7

15 (34.09 %)

1 (6.67 %)

8 (29.63 %)

   8

16 (36.36 %)

0

3 (11.11 %)

  1. * indicates p-values < 0.05 for χ2 testing of the independence across three groups