Table 1 Results of simulations using disease models X1 and X 2, comparing the estimated disease burden between no-heterogeneity and heterogeneity variants. Results indicate the total burden for individuals acutely infected in simulation year 1, with 95% quantile intervals
Disease model [–Variant] | YLD | YLL (95% interval) | DALY (95% interval) | Overestimation of DALY (95% interval) |
|---|---|---|---|---|
X 1 (3 health outcomes, 4 broad age-groups specified for transition from chronic infection to death) | ||||
– No heterogeneity | 75 | 1243 | 1318 | 1.16 (1.11–1.22) |
– Heterogeneitya | 75 | 1060 (1007–1117) | 1135 (1082–1192 | – |
X 2 (4 health outcomes) | ||||
– No heterogeneity | 10750 | 10210 (9380–11090) | 20960 (20140–21740) | 1.04 (1.01–1.08) |
– Heterogeneityb | 11010 | 9074 (8411–9887) | 20090 (19440–20780) | – |