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Table 2 Trends of sepsis incidence and sepsis-related mortality across Spanish regions (autonomous communities) from 2000 to 2013

From: Epidemiological trends of sepsis in the twenty-first century (2000–2013): an analysis of incidence, mortality, and associated costs in Spain

  Incidence (events per 1000 population) Mortality (deaths per 10,000 population)
Regions 2000–2004 2005–2009 2010–2013 p-value 2000–2004 2005–2009 2010–2013 p-value
Andalusia 2.53 (2.52; 2.55) 3.47 (3.45; 3.49) 3.42 (3.4; 3.43) < 0.001 5.8 (5.72; 5.88) 7.75 (7.67; 7.84) 7.89 (7.81; 7.98) < 0.001
Aragon 4 (3.95; 4.05) 4.76 (4.71; 4.82) 4.67 (4.62; 4.73) < 0.001 9.39 (9.14; 9.63) 10.46 (10.21; 10.71) 10.49 (10.25; 10.74) < 0.001
Asturias 3.95 (3.9; 4.01) 4.77 (4.71; 4.83) 5.44 (5.38; 5.5) < 0.001 7.1 (6.87; 7.32) 8.33 (8.09; 8.58) 10.27 (9.99; 10.54) < 0.001
Balearic Islands 3.21 (3.16; 3.26) 4.38 (4.33; 4.44) 4.52 (4.46; 4.58) < 0.001 5.49 (5.27; 5.7) 6.63 (6.41; 6.86) 6.6 (6.39; 6.82) < 0.001
Basque country 3.26 (3.23; 3.3) 4.67 (4.62; 4.71) 5.09 (5.05; 5.13) < 0.001 5.54 (5.4; 5.68) 7.13 (6.97; 7.29) 7.94 (7.78; 8.11) < 0.001
Canary Islands 1.35 (1.33; 1.37) 2.07 (2.04; 2.09) 2.21 (2.19; 2.24) < 0.001 3.34 (3.22; 3.46) 4.94 (4.8; 5.08) 4.97 (4.83; 5.1) < 0.001
Cantabria 4.13 (4.06; 4.21) 4.18 (4.1; 4.25) 4.16 (4.09; 4.23) 0.616 8.22 (7.87; 8.56) 9.32 (8.97; 9.68) 8.65 (8.32; 8.99) 0.096
Castile-La Mancha 4.13 (4.09; 4.18) 5.5 (5.45; 5.55) 5.66 (5.62; 5.71) < 0.001 6.32 (6.15; 6.48) 8.97 (8.79; 9.16) 9.84 (9.64; 10.03) < 0.001
Castille and Leon 4.22 (4.19; 4.26) 6.01 (5.97; 6.05) 6.36 (6.32; 6.41) < 0.001 8.63 (8.47; 8.8) 11.6 (11.41; 11.79) 12.05 (11.86; 12.24) < 0.001
Catalonia 3.86 (3.84; 3.88) 5.14 (5.12; 5.17) 5.59 (5.56; 5.61) < 0.001 6.31 (6.22; 6.4) 8 (7.91; 8.1) 8.11 (8.02; 8.21) < 0.001
Ceuta 2.06 (1.91; 2.2) 3.47 (3.28; 3.66) 2.63 (2.47; 2.79) < 0.001 5.32 (4.56; 6.08) 6.76 (5.91; 7.61) 6.21 (5.43; 7) 0.132
Extremadura 3.03 (2.98; 3.08) 3.9 (3.85; 3.96) 4.66 (4.6; 4.72) < 0.001 5.64 (5.44; 5.84) 8.17 (7.93; 8.41) 9.09 (8.83; 9.34) < 0.001
Galicia 4.4 (4.37; 4.44) 5.55 (5.51; 5.59) 5.87 (5.83; 5.91) < 0.001 8.36 (8.2; 8.51) 10.45 (10.28; 10.62) 10.88 (10.71; 11.06) < 0.001
La Rioja 4.38 (4.27; 4.49) 4.85 (4.74; 4.96) 4.62 (4.52; 4.73) 0.003 6.47 (6.05; 6.9) 6.23 (5.83; 6.62) 6.65 (6.25; 7.06) 0.514
Madrid 3.86 (3.84; 3.89) 5.06 (5.04; 5.09) 5.67 (5.64; 5.7) < 0.001 7.17 (7.07; 7.27) 8.57 (8.47; 8.68) 8.94 (8.84; 9.05) < 0.001
Murcia 2.75 (2.71; 2.79) 3.35 (3.3; 3.39) 3.77 (3.73; 3.82) < 0.001 5.61 (5.42; 5.79) 6.6 (6.41; 6.79) 7.14 (6.95; 7.33) < 0.001
Melilla 2.59 (2.42; 2.77) 3.13 (2.94; 3.32) 3.07 (2.9; 3.25) < 0.001 5.27 (4.49; 6.05) 8.6 (7.61; 9.58) 8.75 (7.81; 9.69) < 0.001
Navarre 2.78 (2.72; 2.84) 3.93 (3.86; 4) 3.72 (3.65; 3.79) < 0.001 4.51 (4.26; 4.76) 7.15 (6.85; 7.46) 6.84 (6.55; 7.13) < 0.001
Valencian community 2.28 (2.26; 2.3) 3.23 (3.2; 3.25) 3.79 (3.76; 3.81) < 0.001 4.74 (4.64; 4.83) 6.49 (6.39; 6.6) 7.39 (7.28; 7.5) < 0.001
p-value < 0.001 < 0.001 < 0.001   < 0.001 < 0.001 < 0.001  
  1. Values were expressed as rate (95% CI)
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