Study reference | Intervention* | Reported ICER (NZ$)** | ICER (NZ$ 2017)** |
---|---|---|---|
Cost-saving interventions | |||
Leung et al. [20] | Pedometer-based promotion in primary care versus time-based activity goals via green prescriptions | Cost-saving | Cost-saving |
Diagnosis and treatment pathways for insomnia for a range of practitioners including: pharmacists, general practitioners (GPs), psychologists, other health professionals, and alternative health practitioners | Cost-saving | Cost-saving | |
Lew et al. [23] | Primary human papillomavirus (HPV) screening with partial genotyping in both unvaccinated women and cohorts offered vaccination | Cost-saving relative to current practice; One strategy (S2a): $20,600 per QALY saved in unvaccinated scenario; $9770 in vaccinated scenario (both compared to next best strategy) (2015 NZ$) | Cost-saving to 20,800 (for S2a strategy) |
Friedman et al. [24] | Proposed national programme to prevent paediatric abusive head trauma (AHT, often known as “shaken baby syndrome”) | Cost-saving in most scenarios, i.e., where reduction in AHT is 30% or more and intervention cost is between $20 and $100 per new-born. However, some estimates were as high as $471,000 per QALY (2012 NZ$) | Cost-saving to 492,000 |
Cost-effective interventions | |||
Gander et al. [25] | Diagnosis and treatment pathways for obstructive sleep apnoea syndrome (OSAS) from GP level through to surgical intervention | $94 per QALY (2005 NZ$) | 121 |
Lake et al. [26] | Campylobacter control in NZ poultry meat supply: interventions at all points from farm to consumer (as per the situation in 2005) | Range: from NZ$1200 per DALY (primary processing interventions) to NZ$43,400 per DALY (irradiation at primary processing stage) (2009 NZ$) | 1360 to 49,300 |
Webb et al. [27] | A “soft regulation” national policy for dietary sodium reduction that combines targeted industry agreements, government monitoring, and public education (modelled on the UK programme) | I$989/DALY (using 2013 I$) | 1480 |
Maddison et al. [28] | Improving exercise capacity and physical activity through a mobile phone / online intervention in addition to usual care, for people with ischaemic heart disease (IHD) | $2690 per QALY (for the 12 month timeframe) (2012 NZ$) | 2810 |
Dalziel et al. [29] | A broad range of interventions to prevent neural tube defects (from targeted promotion of folic acid supplement to voluntary/mandatory folic acid fortification of the food supply) | $2700 per DALY for physician advice for supplement use; $6500 per DALY for a health promotion campaign for supplement use; (both targeted at women around the time of conception) (2006 NZ$) | 3370 and 8120 |
Sopina and Ashton [30] | 18 different cervical cancer screening combinations (e.g., based on usage of the HPV vaccine, screening interval length (3 or 5 years), etc. | $3560 to $10,200 per QALY (for a “no vaccine” base case comparison) (2009 NZ$) | 4040 to 11,540 |
Panattoni et al. [31] | Treatment of acute coronary syndrome with prasugrel if the person is a carrier of the CYP2C19*2 allele (if not a carrier of this allele, the person gets treatment with clopidogrel) | $4480 per QALY when using prasugrel instead of clopidogrel; and $8700 per QALY (if the former is genetically guided) (2009 NZ$). | 5080 and 9880 |
Simms et al. [32] | Strategies for screening for HPV in context of a nonavalent vaccine (“HPV9 vaccine”) | $5000 per LY saved for 5 screens per lifetime (for cohorts offered nonavalent vaccine) (2013 NZ$) | 5170 |
Te Ao et al. [33] | Increasing the use of thrombolysis treatment for ischaemic stroke by increasing hospital presentations and / or increasing use of thrombolysis treatment in hospital | $6640 per QALY (lifetime) and $27,000 (first year) (2010 NZ$) | 7380 and 30,000 |
Te Ao et al. [34] | Acute stroke units in NZ hospitals (as opposed to care on general wards) | $6750 per QALY (lifetime) and $42,800 per QALY (first year) for care in an acute stroke unit vs a general ward (2008 NZ$) | 7960 and 50,500 |
Keall et al. [35] | Package of home modifications to reduce injuries from falls at home | $14,300 per DALY when just considering intervention costs, i.e., no cost offsets (2012 NZ$). | 14,900 |
Milne et al. [36] | Long-term air humidification therapy plus usual care for people with moderate/severe COPD/bronchiectasis | $20,900 per QALY (mean) (2012–2013 NZ$) | 21,600 |
Rush et al. [37] | A multicomponent through-school physical activity and nutrition programme (“Project Energize”) | Range from $22,200 to $30,400 per QALY (depending on age and ethnicity) (2011 NZ$) | 24,100 to 33,100 |
Pinto et al. [38] | Knee/hip osteoarthritis (OA) treatment: manual therapy, exercise therapy, or both, plus usual care | Range from $26,400 per QALY (exercise therapy) to $149,000 (combined therapy) from the health system perspective (2009 NZ$) | 30,000 to 169,000 |
Carrasco et al. [39] | Antiviral stockpiling for future influenza pandemics (relative to no stockpiling) | Approximately US$20,000 per QALY (for the most plausible scenario of 30% of misallocation of antivirals) (2010 US$) | 33,200 |
Not cost-effective interventions | |||
Harris et al. [40] | Planned early start for dialysis treatment based on kidney function for patients with progressive chronic kidney disease. | 72% of results indicated reduced health gain and increased costs. Only 0.3% of iterations gave a positive QALY at under $50,000 per QALY | Not estimated |
Leung et al. [41] | Exercise counselling intervention to enhance smoking cessation | $451,000 per QALY (using 24 week follow-up) (2012 NZ$) | 455,000 |