Skip to main content

Table 2 Age-standardized death rate of liver-related disease in 2008 and 2018 according to underlying and multiple cause of death (UCOD and MCOD) data

From: Changes in liver-related mortality by etiology and sequelae: underlying versus multiple causes of death

 

2008

2018

Rate

Liver-related disease

Deaths

Rate

Deaths

Rate

Difference

Ratio

(95% CI)

Overall

 UCOD

68,037

28.8

90,635

32.5

3.6

1.13

(1.11–1.13)

 MCOD

113,219

48.2

161,312

57.6

9.5

1.20

(1.18–1.20)

 UCOD/MCOD, %

60.1

 

56.2

    

Overall (excluding secondary liver cancer)

 UCOD

66,175

28.0

88,785

31.8

3.80

1.14

(1.12–1.14)

 MCOD

98,657

41.8

133,216

47.7

5.88

1.14

(1.13–1.14)

 UCOD/MCOD, %

67.1

 

66.6

    

Etiology

 Hepatitis C virus

  UCOD

6834

2.8

4127

1.5

−1.3

0.52

(0.50–0.54)

  MCOD

15,707

6.4

15,712

5.6

−0.9

0.86

(0.84–0.88)

  UCOD/MCOD, %

43.5

 

26.3

    

 Other hepatitis

  UCOD

883

0.4

755

0.3

−0.1

0.74

(0.66–0.80)

  MCOD

2280

1.0

2381

0.9

−0.1

0.90

(0.84–0.94)

  UCOD/MCOD, %

38.7

 

31.7

    

 Alcoholic liver disease

  UCOD

14,864

6.2

23,171

8.6

2.4

1.38

(1.35–1.40)

  MCOD

19,530

8.2

30,446

11.2

3.1

1.37

(1.34–1.39)

  UCOD/MCOD, %

76.1

 

76.1

    

 Other diseases of liver

  UCOD

6077

2.6

8507

3.0

0.4

1.17

(1.13–1.20)

  MCOD

15,394

6.6

22,228

8.0

1.4

1.22

(1.19–1.24)

  UCOD/MCOD, %

39.5

 

38.3

    

Sequelae

 Primary liver cancer

  UCOD

18,159

7.8

27,647

9.7

1.9

1.24

(1.22–1.26)

  MCOD

19,666

8.4

30,441

10.7

2.2

1.27

(1.24–1.28)

  UCOD/MCOD, %

92.3

 

90.8

    

 Secondary liver cancer

  UCOD

2071

0.9

2104

0.7

−0.2

0.82

(0.76–0.86)

  MCOD

17,341

7.5

31,676

11.2

3.7

1.49

(1.46–1.51)

  UCOD/MCOD, %

11.9

 

6.6

    

 Cirrhosis

  UCOD

14,993

6.4

19,615

7.0

0.6

1.09

(1.07–1.11)

  MCOD

30,463

12.9

43,165

15.3

2.4

1.18

(1.16–1.20)

  UCOD/MCOD, %

49.2

 

45.4

    

 Esophageal varices

  UCOD

181

0.1

211

0.1

0.0

1.00

(0.80–1.19)

  MCOD

2619

1.1

3663

1.3

0.2

1.22

(1.15–1.27)

  UCOD/MCOD, %

6.9

 

5.8

    

 Hepatic failure

  UCOD

3975

1.7

4498

1.6

−0.1

0.96

(0.91–0.99)

  MCOD

24,578

10.5

27,059

9.7

−0.7

0.93

(0.91–0.94)

  UCOD/MCOD, %

16.2

 

16.6