2008 | 2018 | Rate | |||||
---|---|---|---|---|---|---|---|
Liver-related disease | Deaths | Rate | Deaths | Rate | Difference | Ratio | (95% CI) |
Overall | |||||||
UCOD | 68,037 | 28.8 | 90,635 | 32.5 | 3.6 | 1.13 | (1.11–1.13) |
MCOD | 113,219 | 48.2 | 161,312 | 57.6 | 9.5 | 1.20 | (1.18–1.20) |
UCOD/MCOD, % | 60.1 | 56.2 | |||||
Overall (excluding secondary liver cancer) | |||||||
UCOD | 66,175 | 28.0 | 88,785 | 31.8 | 3.80 | 1.14 | (1.12–1.14) |
MCOD | 98,657 | 41.8 | 133,216 | 47.7 | 5.88 | 1.14 | (1.13–1.14) |
UCOD/MCOD, % | 67.1 | 66.6 | |||||
Etiology | |||||||
Hepatitis C virus | |||||||
UCOD | 6834 | 2.8 | 4127 | 1.5 | −1.3 | 0.52 | (0.50–0.54) |
MCOD | 15,707 | 6.4 | 15,712 | 5.6 | −0.9 | 0.86 | (0.84–0.88) |
UCOD/MCOD, % | 43.5 | 26.3 | |||||
Other hepatitis | |||||||
UCOD | 883 | 0.4 | 755 | 0.3 | −0.1 | 0.74 | (0.66–0.80) |
MCOD | 2280 | 1.0 | 2381 | 0.9 | −0.1 | 0.90 | (0.84–0.94) |
UCOD/MCOD, % | 38.7 | 31.7 | |||||
Alcoholic liver disease | |||||||
UCOD | 14,864 | 6.2 | 23,171 | 8.6 | 2.4 | 1.38 | (1.35–1.40) |
MCOD | 19,530 | 8.2 | 30,446 | 11.2 | 3.1 | 1.37 | (1.34–1.39) |
UCOD/MCOD, % | 76.1 | 76.1 | |||||
Other diseases of liver | |||||||
UCOD | 6077 | 2.6 | 8507 | 3.0 | 0.4 | 1.17 | (1.13–1.20) |
MCOD | 15,394 | 6.6 | 22,228 | 8.0 | 1.4 | 1.22 | (1.19–1.24) |
UCOD/MCOD, % | 39.5 | 38.3 | |||||
Sequelae | |||||||
Primary liver cancer | |||||||
UCOD | 18,159 | 7.8 | 27,647 | 9.7 | 1.9 | 1.24 | (1.22–1.26) |
MCOD | 19,666 | 8.4 | 30,441 | 10.7 | 2.2 | 1.27 | (1.24–1.28) |
UCOD/MCOD, % | 92.3 | 90.8 | |||||
Secondary liver cancer | |||||||
UCOD | 2071 | 0.9 | 2104 | 0.7 | −0.2 | 0.82 | (0.76–0.86) |
MCOD | 17,341 | 7.5 | 31,676 | 11.2 | 3.7 | 1.49 | (1.46–1.51) |
UCOD/MCOD, % | 11.9 | 6.6 | |||||
Cirrhosis | |||||||
UCOD | 14,993 | 6.4 | 19,615 | 7.0 | 0.6 | 1.09 | (1.07–1.11) |
MCOD | 30,463 | 12.9 | 43,165 | 15.3 | 2.4 | 1.18 | (1.16–1.20) |
UCOD/MCOD, % | 49.2 | 45.4 | |||||
Esophageal varices | |||||||
UCOD | 181 | 0.1 | 211 | 0.1 | 0.0 | 1.00 | (0.80–1.19) |
MCOD | 2619 | 1.1 | 3663 | 1.3 | 0.2 | 1.22 | (1.15–1.27) |
UCOD/MCOD, % | 6.9 | 5.8 | |||||
Hepatic failure | |||||||
UCOD | 3975 | 1.7 | 4498 | 1.6 | −0.1 | 0.96 | (0.91–0.99) |
MCOD | 24,578 | 10.5 | 27,059 | 9.7 | −0.7 | 0.93 | (0.91–0.94) |
UCOD/MCOD, % | 16.2 | 16.6 |