20-44 years | 45-64 years | 65-74 years | 75+ years | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Liver-related disease | RD | RR | (95% CI) | RD | RR | (95% CI) | RD | RR | (95% CI) | RD | RR | (95% CI) |
Overall | ||||||||||||
UCOD | 0.52 | 1.11 | (1.06–1.15) | 2.89 | 1.06 | (1.04–1.08) | 18.24 | 1.29 | (1.26–1.31) | 9.65 | 1.12 | (1.09–1.13) |
MCOD | 0.98 | 1.13 | (1.09–1.15) | 9.38 | 1.14 | (1.12–1.14) | 37.26 | 1.34 | (1.31–1.35) | 32.15 | 1.21 | (1.19–1.22) |
Overall (excluding secondary liver cancer) | ||||||||||||
UCOD | 0.54 | 1.11 | (1.07–1.15) | 2.81 | 1.06 | (1.04–1.07) | 18.59 | 1.31 | (1.27–1.33) | 11.48 | 1.15 | (1.12–1.17) |
MCOD | 0.56 | 1.07 | (1.04–1.10) | 4.69 | 1.07 | (1.06–1.08) | 28.44 | 1.31 | (1.28–1.33) | 18.67 | 1.16 | (1.13–1.17) |
Etiology | ||||||||||||
Hepatitis C virus | ||||||||||||
UCOD | −0.26 | 0.37 | (0.30–0.43) | −3.43 | 0.47 | (0.44–0.48) | −0.21 | 0.94 | (0.85–1.03) | −1.54 | 0.54 | (0.46–0.60) |
MCOD | −0.31 | 0.68 | (0.61–0.74) | −3.74 | 0.75 | (0.72–0.76) | 6.24 | 1.75 | (1.65–1.85) | −1.64 | 0.77 | (0.71–0.83) |
Other hepatitis | ||||||||||||
UCOD | −0.01 | 0.86 | (0.60–1.11) | −0.19 | 0.69 | (0.59–0.77) | −0.10 | 0.85 | (0.65–1.03) | −0.28 | 0.71 | (0.55–0.86) |
MCOD | −0.03 | 0.88 | (0.72–1.04) | −0.36 | 0.79 | (0.72–0.84) | 0.34 | 1.20 | (1.04–1.35) | −0.08 | 0.96 | (0.82–1.09) |
Alcoholic liver disease | ||||||||||||
UCOD | 0.90 | 1.43 | (1.35–1.51) | 4.45 | 1.36 | (1.32–1.39) | 4.33 | 1.43 | (1.35–1.50) | 1.49 | 1.31 | (1.19–1.41) |
MCOD | 1.05 | 1.40 | (1.33–1.47) | 5.41 | 1.33 | (1.29–1.35) | 6.87 | 1.52 | (1.45–1.58) | 2.64 | 1.40 | (1.30–1.50) |
Other diseases of liver | ||||||||||||
UCOD | −0.10 | 0.82 | (0.71–0.91) | −0.09 | 0.98 | (0.92–1.02) | 2.42 | 1.41 | (1.31–1.51) | 3.60 | 1.49 | (1.38–1.58) |
MCOD | 0.03 | 1.02 | (0.94–1.08) | 0.64 | 1.07 | (1.03–1.09) | 6.32 | 1.45 | (1.38–1.50) | 7.66 | 1.43 | (1.37–1.49) |
Sequelae | ||||||||||||
Primary liver cancer | ||||||||||||
UCOD | 0.01 | 1.03 | (0.89–1.15) | 1.74 | 1.19 | (1.15–1.22) | 10.03 | 1.50 | (1.44–1.55) | 5.31 | 1.15 | (1.11–1.18) |
MCOD | 0.00 | 1.00 | (0.87–1.13) | 2.11 | 1.21 | (1.17–1.24) | 11.37 | 1.53 | (1.47–1.57) | 6.56 | 1.17 | (1.13–1.21) |
Secondary liver cancer | ||||||||||||
UCOD | −0.02 | 0.46 | (0.20–0.71) | 0.05 | 1.08 | (0.95–1.21) | −0.25 | 0.89 | (0.78–0.99) | −1.78 | 0.69 | (0.62–0.75) |
MCOD | 0.31 | 1.56 | (1.40–1.72) | 4.73 | 1.67 | (1.61–1.72) | 9.87 | 1.44 | (1.39–1.49) | 13.96 | 1.38 | (1.33–1.42) |
Cirrhosis | ||||||||||||
UCOD | 0.01 | 1.01 | (0.91–1.10) | 0.62 | 1.07 | (1.03–1.10) | 1.91 | 1.12 | (1.06–1.16) | 2.79 | 1.13 | (1.08–1.17) |
MCOD | 0.00 | 1.00 | (0.93–1.06) | 1.77 | 1.09 | (1.06–1.11) | 10.97 | 1.35 | (1.30–1.38) | 9.97 | 1.25 | (1.21–1.29) |
Esophageal varices | ||||||||||||
UCOD | −0.01 | 0.74 | (0.28–1.19) | 0.01 | 1.11 | (0.80–1.40) | 0.01 | 1.05 | (0.54–1.55) | −0.01 | 0.93 | (0.49–1.37) |
MCOD | 0.01 | 1.04 | (0.88–1.19) | 0.36 | 1.17 | (1.09–1.24) | 0.96 | 1.58 | (1.37–1.77) | 0.39 | 1.24 | (1.05–1.41) |
Hepatic failure | ||||||||||||
UCOD | 0.00 | 1.00 | (0.84–1.14) | −0.28 | 0.89 | (0.83–0.94) | 0.12 | 1.03 | (0.93–1.12) | 0.06 | 1.01 | (0.92–1.10) |
MCOD | 0.06 | 1.03 | (0.96–1.09) | −1.23 | 0.92 | (0.89–0.94) | −1.03 | 0.96 | (0.92–0.99) | −3.35 | 0.89 | (0.85–0.92) |