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Table 3 Median chance-corrected concordance (%) for SSP and PCVA, by age group with and without HCE

From: Simplified Symptom Pattern Method for verbal autopsy analysis: multisite validation study using clinical diagnostic gold standards

  

SSP

PCVA

  

Median

95% UI

Median

95% UI

Adult

No HCE

38.0

(37.8, 38.1)

29.7

(29.4, 29.8)

 

HCE

45.8

(45.7, 45.9)

44.6

(44.3, 44.8)

Child

No HCE

46.8

(46.5, 47.3)

36.3

(35.9, 36.6)

 

HCE

51.5

(51.1, 51.9)

47.8

(47.1, 48.3)

Neonate

No HCE

30.4

(30.0, 30.7)

27.6

(27.2, 28.0)

 

HCE

32.5

(32.0, 33.0)

33.3

(32.8, 33.7)

  1. The median chance-corrected concordance is computed as the median across 500 splits of the mean chance-corrected concordance across causes. These results show how SSP outperforms physicians in individual cause assignment in every situation where head-to-head comparison is possible, except for the neonatal module with the HCE information added. In the neonatal module, SSP cannot be directly compared to PCVA since PCVA analysis could only be conducted for six neonate causes, while SSP can predict for 11 causes.