Table 2 Validation results for the InterVA model and PCVA against the HCOD in diagnosing the cause of death for the five most common causes of death among 145 adults
Causes of death | Sensitivity (%) (95% CI) | PPV (%) (95% CI) | Specificity (%) (95% CI) | NPV (%) (95% CI) |
|---|---|---|---|---|
InterVA | ||||
HIV/AIDS-related death | 70 (5-84) | 61 (43-76) | 87 (79-92) | 91 (84-92) |
Cardiovascular | 52 (34-69) | 57 (37-75) | 88 (81-94) | 86 (78-92) |
Tuberculosis (pulmonary) | 83 (36-100) | 28 (10-54) | 91 (85-95) | 99 (96-100) |
Meningitis | 43 (10-82) | 33 (8-70) | 96 (91-99) | 97 (93-99) |
Diabetes | 63 (25-92) | 83 (36-100) | 99 (96-100) | 98 (94-100) |
PCVA | ||||
HIV/AIDS-related death | 88 (72-97) | 80 (64-92) | 94 (88-98) | 96 (91-99) |
Cardiovascular | 70 (51-84) | 82 (63-94) | 96 (90-99) | 91 (85-95) |
Tuberculosis (pulmonary) | 100 (54-100) | 55 (23-83) | 96 (92-99) | 100 (97-100) |
Meningitis | 43 (10-82) | 60 (15-95) | 99 (95-100) | 97 (93-99) |
Diabetes | 100 (63-100) | 57 (29-82) | 96 (91-99) | 100 (97-100) |