Flexible parametric methods for calculating life expectancy in small populations

Table 2 Characteristics of 2012 sample population used for the analysis

Characteristic	Intellectual disabilities N (%)/Median (range)		No intellectual disabilities N (%)/Median (range)
Total	16,904	(100.0)	434,318^a	(100.0)
Age (at baseline^b)	36.0	(10–100)	44.0	(10–109)
Gender
Male	9,451	(55.9)	213,678	(49.2)
Female	7,453	(44.1)	220,640	(50.8)
Ethnicity
White	12,796	(75.7)	297,320	(68.5)
South Asian	459	(2.7)	15,425	(3.6)
Black	374	(2.2)	11,257	(2.6)
Other	456	(2.7)	16,428	(3.8)
Not known	2819	(16.7)	93,888	(21.6)
Type 2 diabetes^c
Present	1006	(6.0)	23,381	(5.4)
Died	193	(1.1)	4296	(1.0)
Most common genetic syndromes
Down syndrome	2049	(12.1)
Fragile X syndrome	323	(1.9)
Tuberous sclerosis	158	(0.9)
William syndrome	70	(0.4)
Prader-Willi syndrome	61	(0.4)

^aIncludes 553 individuals from the intellectual disability sample who changed status (i.e. had their first intellectual disability diagnosis) during the observation window and a further 1339 individuals who were registered but had their first intellectual disability diagnosis outside the window (i.e. after 2012)
^bIndividuals entered the cohort on 01/01/2012 or sometime during 2012 if registered or changed status during the observation period
^cIncludes 1871 individuals who changed T2DM status (i.e. had a T2DM diagnosis) during the observation window

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